PUBLICATIONS












Ostfeld I, Ben-Zeev T, Zamir A, Levi C, Gepner Y, Springer S, Hoffman JR. Role of β-Alanine Supplementation on Cognitive Function, Mood, and Physical Function in Older Adults; Double-Blind Randomized Controlled Study. Nutrients. 2023 Feb 12;15(4):923. doi: 10.3390/nu15040923. PMID: 36839281; PMCID: PMC9960300.
Kfir A, Lahav Y, Gepner Y. Cross-Validation of a New General Population Resting Metabolic Rate Prediction Equation Based on Body Composition. Nutrients. 2023 Feb 4;15(4):805. doi: 10.3390/nu15040805. PMID: 36839163; PMCID: PMC9960966.
Sheinboim D, Parikh S, Manich P, Markus I, Dahan S, Parikh R, Stubbs E, Cohen G, Zemser-Werner V, Bell RE, Arciniegas Ruiz S, Percik R, Brenner R, Leibou S, Vaknine H, Arad G, Gerber Y, Keinan Boker L, Shimony T, Bikovski L, Goldstein N, Constantini K, Labes S, Mordechai S, Doron H, Ionescu A, Ziv T, Nizri E, Choshen G, Eldar-Finkelman H, Tabach Y, Helman A, Ben-Eliyahu S, Erez N, Perlson E, Geiger T, Ben-Zvi D, Khaled M, Gepner Y, Levy C. An exercise-induced metabolic shield in distant organs blocks cancer progression and metastatic dissemination. Cancer Res. 2022 Sep 9:CAN-22-0237. doi: 10.1158/0008-5472.CAN-22-0237. Epub ahead of print. PMID: 36084256.
Nachman D, Eisenkraft A, Goldstein N, Ben-Ishay A, Fons M, Merin R, Gepner Y. Influence of Sex, BMI, and Skin Color on the Accuracy of Non-Invasive Cuffless Photoplethysmography-Based Blood Pressure Measurements. Front Physiol. 2022 Jun 29;13:911544. doi: 10.3389/fphys.2022.911544. PMID: 35846008; PMCID: PMC9277111.
Markus I, Constantini K, Goldstein N, Amedi R, Bornstein Y, Stolkovsky Y, Vidal M, Lev-Ari S, Balaban R, Leibou S, Blumenfeld-Katzir T, Ben-Eliezer N, Peled D, Assaf Y, Jensen D, Constantini N, Dubnov-Raz G, Halperin I, Gepner Y. Age Differences in Recovery Rate Following an Aerobic-Based Exercise Protocol Inducing Muscle Damage Among Amateur, Male Athletes. Front Physiol. 2022 Jun 13;13:916924. doi: 10.3389/fphys.2022.916924. PMID: 35774290; PMCID: PMC9239318.
Zelber-Sagi S, Grinshpan LS, Ivancovsky-Wajcman D, Goldenshluger A, Gepner Y. One size does not fit all; practical, personal tailoring of the diet to NAFLD patients. Liver Int. 2022 Aug;42(8):1731-1750. doi: 10.1111/liv.15335. Epub 2022 Jun 21. PMID: 35675167.
Goldenshluger A, Maor T, Via-Kagan R, Zelekha O, Gepner Y. Short-Term Changes in Mental, Physical, and Social Factors After Metabolic Bariatric Surgery in Adolescents: A Nationwide Prospective Cohort Study. Front Nutr. 2022 May 12;9:878202. doi: 10.3389/fnut.2022.878202. PMID: 35634384; PMCID: PMC9133935.
Gepner Y, Mofaz M, Oved S, Yechezkel M, Constantini K, Goldstein N, Eisenkraft A, Shmueli E, Yamin D. Utilizing wearable sensors for continuous and highly-sensitive monitoring of reactions to the BNT162b2 mRNA COVID-19 vaccine. Commun Med (Lond). 2022 Mar 14;2:27. doi: 10.1038/s43856-022-00090-y. PMID: 35603274; PMCID: PMC9053261.
Donini LM, Busetto L, Bischoff SC, Cederholm T, Ballesteros-Pomar MD, Batsis JA, Bauer JM, Boirie Y, Cruz-Jentoft AJ, Dicker D, Frara S, Frühbeck G, Genton L, Gepner Y, Giustina A, Gonzalez MC, Han HS, Heymsfield SB, Higashiguchi T, Laviano A, Lenzi A, Nyulasi I, Parrinello E, Poggiogalle E, Prado CM, Salvador J, Rolland Y, Santini F, Serlie MJ, Shi H, Sieber CC, Siervo M, Vettor R, Villareal DT, Volkert D, Yu J, Zamboni M, Barazzoni R. Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement. Clin Nutr. 2022 Apr;41(4):990-1000. doi: 10.1016/j.clnu.2021.11.014. Epub 2022 Feb 22. PMID: 35227529.
Hoffman JR, Ostfeld I, Zamir A, Amedi R, Fonville TR, Horstemeyer MF, Gepner Y. Examination of Cognitive Function, Neurotrophin Concentrations, and both Brain and Systemic Inflammatory Markers Following a Simulated Game of American Football. J Strength Cond Res. 2022 Mar 1;36(3):686-694. doi: 10.1519/JSC.0000000000004218. PMID: 35180187.
Yaskolka Meir A, Keller M, Bernhart SH, Rinott E, Tsaban G, Zelicha H, Kaplan A, Schwarzfuchs D, Shelef I, Gepner Y, Li J, Lin Y, Blüher M, Ceglarek U, Stumvoll M, Stadler PF, Stampfer MJ, Kovacs P, Liang L, Shai I. Lifestyle weight-loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial. Clin Epigenetics. 2021 Mar 4;13(1):48. doi: 10.1186/s13148-021-01038-0. PMID: 33663610; PMCID: PMC7934393.
Tsaban G, Bilitzky-Kopit A, Yaskolka Meir A, Zelicha H, Gepner Y, Shelef I, Orr O, Chassidim Y, Sarusi B, Ceglarek U, Stumvoll M, Blüher M, Stampfer MJ, Shai I, Schwarzfuchs D. The Effect of Weight-Loss Interventions on Cervical and Chin Subcutaneous Fat Depots; the CENTRAL Randomized Controlled Trial. Nutrients. 2021 Oct 27;13(11):3827. doi: 10.3390/nu13113827. PMID: 34836081; PMCID: PMC8617936.
Goldstein N, Tsuneki H, Bhandarkar N, Aimaretti E, Haim Y, Kon K, Sato K, Wada T, Liberty IF, Kirshtein B, Dukhno O, Maixner N, Gepner Y, Sasaoka T, Rudich A. Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross-sectional study. Obesity (Silver Spring). 2021 Nov;29(11):1857-1867. doi: 10.1002/oby.23262. Epub 2021 Sep 2. PMID: 34472713.
Dean Nachman, Adi Gilan, Nir Goldstein, Keren Constantini, Romi Littman, Arik Eisenkraft, Ehud Grossman, Yftach Gepner, Twenty-Four-Hour Ambulatory Blood Pressure Measurement Using a Novel Noninvasive, Cuffless, Wireless Device, American Journal of Hypertension, Volume 34, Issue 11, November 2021, Pages 1171–1180, https://doi.org/10.1093/ajh/hpab095
D Nachman, A Eisenkraft, Y Maor, K Constantini, G Goldstein, R Levy, M Halberthal, N A Horowitz, R Golan, E Rosenberg, E Lavon, O Cohen, G Shapira, N Shomron, Y Gepner, Continuous monitoring of advanced hemodynamic parameters shows early cardiovascular changes in a cohort of 492 COVID-19 hospitalized patients, European Heart Journal, Volume 42, Issue Supplement_1, October 2021, ehab724.3090, https://doi.org/10.1093/eurheartj/ehab724.3090
Yaskolka Meir A, Keller M, Müller L, Bernhart SH, Tsaban G, Zelicha H, Rinott E, Kaplan A, Gepner Y, Shelef I, Schwarzfuchs D, Ceglarek U, Stadler P, Blüher M, Stumvoll M, Kovacs P, Shai I. Effects of lifestyle interventions on epigenetic signatures of liver fat: Central randomized controlled trial. Liver Int. 2021 Sep;41(9):2101-2111. doi: 10.1111/liv.14916. Epub 2021 May 28. PMID: 33938135.
Parikh R, Sorek E, Parikh S, Michael K, Bikovski L, Tshori S, Shefer G, Mingelgreen S, Zornitzki T, Knobler H, Chodick G, Mardamshina M, Boonman A, Kronfeld-Schor N, Bar-Joseph H, Ben-Yosef D, Amir H, Pavlovsky M, Matz H, Ben-Dov T, Golan T, Nizri E, Liber D, Liel Y, Brenner R, Gepner Y, Karnieli-Miller O, Hemi R, Shalgi R, Kimchi T, Percik R, Weller A, Levy C. Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior. Cell Rep. 2021 Aug 24;36(8):109579. doi: 10.1016/j.celrep.2021.109579. PMID: 34433056.
Kachel E, Constantini K, Nachman D, Carasso S, Littman R, Eisenkraft A, Gepner Y. A Pilot Study of Blood Pressure Monitoring After Cardiac Surgery Using a Wearable, Non-invasive Sensor. Front Med (Lausanne). 2021 Aug 5;8:693926. doi: 10.3389/fmed.2021.693926. PMID: 34422859; PMCID: PMC8375406.
Goldenshluger A, Constantini K, Goldstein N, Shelef I, Schwarzfuchs D, Zelicha H, Yaskolka Meir A, Tsaban G, Chassidim Y, Gepner Y. Effect of Dietary Strategies on Respiratory Quotient and Its Association with Clinical Parameters and Organ Fat Loss: A Randomized Controlled Trial. Nutrients. 2021 Jun 29;13(7):2230. doi: 10.3390/nu13072230. PMID: 34209600; PMCID: PMC8308467.
Nachman D, Gilan A, Goldstein N, Constantini K, Littman R, Eisenkraft A, Grossman E, Gepner Y. 24-hour Ambulatory Blood Pressure Measurement using a Novel Non-Invasive, Cuff-less, Wireless Device. Am J Hypertens. 2021 Jun 18:hpab095. doi: 10.1093/ajh/hpab095. Epub ahead of print. PMID: 34143867.
Yaskolka Meir A, Keller M, Müller L, Bernhart SH, Tsaban G, Zelicha H, Rinott E, Kaplan A, Gepner Y, Shelef I, Schwarzfuchs D, Ceglarek U, Stadler P, Blüher M, Stumvoll M, Kovacs P, Shai I. Effects of lifestyle interventions on epigenetic signatures of liver fat: CENTRAL randomized controlled trial. Liver Int. 2021 May 3. doi: 10.1111/liv.14916.
Constantini K, Markus I, Epel N, Jakobovich R, Gepner Y, Lev-Ari S. Continued Participation of Israeli Adolescents in Online Sports Programs during the COVID-19 Pandemic Is Associated with Higher Resilience. Int J Environ Res Public Health. 2021 Apr 20;18(8):4386. doi: 10.3390/ijerph18084386.
Lev-Ari S, Gepner Y, Goldbourt U. Dissatisfaction with Married Life in Men Is Related to Increased Stroke and All-Cause Mortality. J Clin Med. 2021 Apr 16;10(8):1729. doi: 10.3390/jcm10081729.
Yaskolka Meir A, Keller M, Bernhart SH, Rinott E, Tsaban G, Zelicha H, Kaplan A, Schwarzfuchs D, Shelef I, Gepner Y, Li J, Lin Y, Blüher M, Ceglarek U, Stumvoll M, Stadler PF, Stampfer MJ, Kovacs P, Liang L, Shai I. Lifestyle weight-loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial. Clin Epigenetics. 2021 Mar 4;13(1):48. doi: 10.1186/s13148-021-01038-0.
Gepner Y, Goldstein N, Shelef I, Schwarzfuchsc D, Zelicha H, Yaskolka Meir A, Tsaban G, Grossman E. Dissociation between long-term weight loss intervention and blood pressure; an 18-month randomized controlled trial in Jewish Population. Journal of general medicine. In press
Markus I, Constantini K, Hoffman JR, Bartolomei S, Gepner Y. Exercise induced muscle damage – mechanism, assessment and nutritional factors to accelerate recovery. European Journal of Applied physiology. 2021 Jan 8. doi: 10.1007/s00421-020-04566-4
Lahav Y, Goldstein N, Gepner Y. Comparison of body composition assessment across body mass index categories by two multifrequency bioelectrical impedance analysis devices and dual-energy X-ray absorptiometry in clinical settings. European Journal of Clinical Nutrition. 2021 Jan 22. doi: 10.1038/s41430-020-00839-5.
Keller M et al. DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial. Genome Med. 2020;12(1). doi:10.1186/s13073-020-00794-7
Wells AJ et al. Effect of β-Alanine Supplementation on Monocyte Recruitment and Cognition During a 24-Hour Simulated Military Operation. J strength Cond Res. 2020;34(11):3042-3054. doi:10.1519/JSC.0000000000003809
Nachman D, Constantini K, Poris G, Wagnert-Avraham L, Gertz SD, Littman R, Kabakov E, Eisenkraft A, Gepner Y. Wireless, non-invasive, wearable device for continuous remote monitoring of hemodynamic parameters in a swine model of controlled hemorrhagic shock. Sci Rep. 2020;10(1). doi:10.1038/s41598-020-74686-6
Nachman D, Gepner Y, Goldstein N, Kabakov E, Ishay A Ben, Littman R, Azmon Y, Jaffe E, Eisenkraft A. Comparing blood pressure measurements between a photoplethysmography-based and a standard cuff-based manometry device. Sci Rep. 2020;10(1). doi:10.1038/s41598-020-73172-3
Goldstein N et al. Higher Mast Cell Accumulation in Human Adipose Tissues Defines Clinically Favorable Obesity Sub-Phenotypes. Cells. 2020;9(6). doi:10.3390/cells9061508
Hoffman JR, Markus I, Dubnov-Raz G, Gepner Y. Ergogenic Effects of 8 Days of Sceletium Tortuosum Supplementation on Mood, Visual Tracking, and Reaction in Recreationally Trained Men and Women. J strength Cond Res. 2020;34(9):2476-2481. doi:10.1519/JSC.0000000000003693
Coker NA, Wells AJ, Gepner Y. Effect of Heat Stress on Measures of Running Performance and Heart Rate Responses During a Competitive Season in Male Soccer Players. J strength Cond Res. 2020;34(4):1141-1149. doi:10.1519/JSC.0000000000002441
Varanoske AN, Wells AJ, Boffey D, et al. Effects of High-Dose, Short-Duration β-Alanine Supplementation on Cognitive Function, Mood, and Circulating Brain-Derived Neurotropic Factor (BDNF) in Recreationally-Active Males Before Simulated Military Operational Stress. J Diet Suppl. 2020. doi:10.1080/19390211.2020.1733730
Gepner Y, Hoffman JR, Hoffman MW, Zelicha H, Cohen H, Ostfeld I. Association between circulating inflammatory markers and marksmanship following intense military training. J R Army Med Corps. 2019;165(6):391-394. doi:10.1136/jramc-2018-001084
Hoffman, J. R. et al. The Effect of 2 Weeks of Inactivated Probiotic Bacillus coagulans on Endocrine, Inflammatory, and Performance Responses During Self-Defense Training in Soldiers. J. Strength Cond. Res. 1 (2019). doi:10.1519/JSC.0000000000003265
Gepner, Y., Varanoske, A. N., Boffey, D. & Hoffman, J. R. Benefits of β-hydroxy-β-methylbutyrate supplementation in trained and untrained individuals. Res. Sport. Med. 27, 204–218 (2019).
Gepner, Y. et al. The beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat content. J. Hepatol. (2019). doi:10.1016/j.jhep.2019.04.013
Hoffman, J. R., Rathmacher, J. A., Robinson, J., Gepner, Y. & Cohen, H. The Effect of β-Alanine Supplementation on Carnosine and Histidine Content in the Hippocampus of 14-Month Old Rats. Appl. Physiol. Nutr. Metab. apnm-2019-0102 (2019). doi:10.1139/apnm-2019-0102
Boffey, D. et al. The Physiology and Biomechanics of Load Carriage Performance. Mil. Med. 184, e83–e90 (2019).
Hoffman, J. R., Gepner, Y. & Cohen, H. β-Alanine supplementation reduces anxiety and increases neurotrophin expression in both young and older rats. Nutr. Res. 62, 51–63 (2019).
Gepner, Y. et al. Association between circulating inflammatory markers and marksmanship following intense military training. J. R. Army Med. Corps jramc-2018-001084 (2018). doi:10.1136/jramc-2018-001084
Zelicha, H. et al. Changes of renal sinus fat and renal parenchymal fat during an 18-month randomized weight loss trial. Clin. Nutr. 37, 1145–1153 (2018).
Gepner, Y. et al. Effect of Distinct Lifestyle Interventions on Mobilization of Fat Storage Pools. Circulation 137, 1143–1157 (2018).
Hoffman, J. R. et al. Effect of High-Dose, Short-Duration β-Alanine Supplementation on Circulating IL-10 Concentrations During Intense Military Training. J. Strength Cond. Res. 32, 2978–2981 (2018).
Golan, R. et al. Effect of wine on carotid atherosclerosis in type 2 diabetes: a 2-year randomized controlled trial. Eur. J. Clin. Nutr. 72, 871–878 (2018).
Varanoske, A. N. et al. Effects of β-alanine supplementation on physical performance, cognition, endocrine function, and inflammation during a 24 h simulated military operation. Physiol. Rep. 6, e13938 (2018).
Coker, N. A., Wells, A. J. & Gepner, Y. The Effect of Heat Stress on Measures of Running Performance and Heart Rate Responses During A Competitive Season in Male Soccer Players. J. Strength Cond. Res. 1 (2018). doi:10.1519/JSC.0000000000002441
Tene, L. et al. The effect of long-term weight-loss intervention strategies on the dynamics of pancreatic-fat and morphology: An MRI RCT study. Clin. Nutr. ESPEN 24, 82–89 (2018).
Golan, R., Gepner, Y. & Shai, I. Wine and Health–New Evidence. Eur. J. Clin. Nutr. (2018). doi:10.1038/s41430-018-0309-5
Serfaty, D. et al. Abdominal fat sub-depots and energy expenditure: Magnetic resonance imaging study. Clin. Nutr. 36, 804–811 (2017).
Haim, Y. et al. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype. Mol. Metab. 6, 725–736 (2017).
Gepner, Y. et al. Combined effect of Bacillus coagulans GBI-30, 6086 and HMB supplementation on muscle integrity and cytokine response during intense military training. J. Appl. Physiol. 123, 11–18 (2017).
Gordon, J. A. et al. Comparisons in the Recovery Response From Resistance Exercise Between Young and Middle-Aged Men. J. Strength Cond. Res. 31, 3454–3462 (2017).
Tsaban, G. et al. Dynamics of intrapericardial and extrapericardial fat tissues during long-term, dietary-induced, moderate weight loss. Am. J. Clin. Nutr. 106, 984–995 (2017).
Golan, R. et al. Effects of initiating moderate wine intake on abdominal adipose tissue in adults with type 2 diabetes: a 2-year randomized controlled trial. Public Health Nutr. 20, 549–555 (2017).
Yaskolka Meir, A. et al. Intrahepatic fat, abdominal adipose tissues, and metabolic state: magnetic resonance imaging study. Diabetes. Metab. Res. Rev. 33, e2888 (2017).
Gepner, Y. et al. Intramyocellular triacylglycerol accumulation across weight loss strategies; Sub-study of the CENTRAL trial. PLoS One 12, e0188431 (2017).
Redd, M. J. et al. The effect of HMB ingestion on the IGF-I and IGF binding protein response to high intensity military training. Growth Horm. IGF Res. 32, 55–59 (2017).
Arroyo, E. et al. Tumor necrosis factor-alpha and soluble TNF-alpha receptor responses in young vs. middle-aged males following eccentric exercise. Exp. Gerontol. 100, 28–35 (2017).
Slutsky, N. et al. Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity. Int. J. Obes. 40, 912–920 (2016).
Gepner, Y. et al. Differential Effect of Initiating Moderate Red Wine Consumption on 24-h Blood Pressure by Alcohol Dehydrogenase Genotypes: Randomized Trial in Type 2 Diabetes. Am. J. Hypertens. 29, 476–483 (2016).
Gepner, Y. et al. Higher visceral adiposity is associated with an enhanced early thermogenic response to carbohydrate-rich food. Clin. Nutr. 35, 422–427 (2016).
Yaskolka Meir, A. et al. Intermuscular adipose tissue and thigh muscle area dynamics during an 18-month randomized weight loss trial. J. Appl. Physiol. 121, 518–527 (2016).
Hoffman, J. R. et al. β-Hydroxy-β-methylbutyrate attenuates cytokine response during sustained military training. Nutr. Res. 36, 553–563 (2016).
Henkin, Y., Kovsan, J., Gepner, Y. & Shai, I. Diets and morbid tissues – history counts, present counts. Br. J. Nutr. 113, S11–S18 (2015).
Gepner, Y. et al. Effects of Initiating Moderate Alcohol Intake on Cardiometabolic Risk in Adults With Type 2 Diabetes. Ann. Intern. Med. 163, 569 (2015).
Haim, Y. et al. Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1. Autophagy 11, 2074–2088 (2015).
Golan, R. et al. Abdominal Superficial Subcutaneous Fat: A putative distinct protective fat subdepot in type 2 diabetes. Diabetes Care 35, 640–647 (2012).
Bluher, M. et al. Two Patterns of Adipokine and Other Biomarker Dynamics in a Long-Term Weight Loss Intervention. Diabetes Care 35, 342–349 (2012).
Canfi, A. et al. Effect of changes in the intake of weight of specific food groups on successful body weight loss during a multi-dietary strategy intervention trial. J. Am. Coll. Nutr. 30, 491–501 (2011).
Leichtle, A. B. et al. Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men. Am. J. Clin. Nutr. 94, 1189–1195 (2011).